evidence_index

Evidence-based research

Every review from The NAD Review, tied to primary research or official labeling — grouped by the question you arrived with.

therapy

NAD+ therapy: routes, evidence & cost

IV, injection, nasal, patch and liposomal NAD+ — what each route can actually show for itself, and what it costs.

NAD+ Therapy for Energy, Focus & Longevity: The EvidenceAn honest, citation-backed look at what NAD+ therapy can and cannot do for energy, focus, and longevity — and where the evidence runs out.
NAD+ IV Therapy: Evidence, Benefits & What It CostsWhat the human evidence actually shows for NAD+ IV therapy, the benefits clinics promise vs. what's proven, and a realistic look at the cost.
What Is a NAD+ Injection? The Definition, and the EvidenceA NAD+ injection is a compounded shot of NAD+ given under the skin or into muscle. What it is, what it costs, and why no human trial supports it.
Liposomal NAD+: Does Oral Absorption Really Work?Liposomal NAD+ is sold as an oral shortcut past the gut. We check what absorption data exists — and the bioavailability claims are mostly brand-made.
NAD+ Nasal Spray: Can It Absorb Through the Nose?NAD+ nasal sprays promise needle-free absorption. The honest answer: intranasal NAD+ is essentially unstudied in humans. Here's what the evidence shows.
NAD+ Patches: Do Transdermal Patches Deliver Anything?NAD+ patches promise needle-free absorption through the skin. The honest answer: the skin barrier blocks large, charged molecules like NAD+. Here's the data.
How Long Does NAD+ IV Therapy Last?Clinics quote 7–14 days, but that number is practitioner convention, not trial-derived. Here's what's actually known about how long an NAD+ IV lasts.
What NAD+ Actually Costs: IV Therapy, Injections and OralNAD+ IV runs $250–$1,500 a session; at-home injections $150–$400 a month; oral precursors $20–$40. None is insurance-covered, and price doesn't track evidence.
Is NAD+ Therapy Worth It? An Evidence-Based Buyer GuideAn honest, evidence-based look at whether NAD+ therapy is worth the cost — who might benefit, who should skip it, and where the trials actually land.
NAD+ IV vs Injection vs Oral: Which Delivery Works Best?IV, subcutaneous injection, or oral NAD+ — the bioavailability ranking is real, but higher blood NAD+ isn't proven to mean better outcomes.
NAD+ Injections at Home vs Near Me: How to ChooseYou probably don't need a clinic. How at-home telehealth NAD+ injections work, how to vet any provider, and real 2026 costs for both routes.

nad_partners

affiliate partners

Reading up before you buy?

The routes above are sold by telehealth clinics. These are the NAD+ programs we partner with — compare them against the evidence, not the ad copy.

Compare every NAD+ provider ↗

We earn a commission if you start care through these links, at no extra cost to you. Read the full disclosure.

products

Products & buying guides

Ranked buying guides and single-product reviews of the supplements people actually shop.

precursors

Precursors: NMN, NR & alternatives

The head-to-heads. Which precursor has human trials behind it, and which has a marketing budget.

conditions

Conditions & goals

What the evidence says when NAD+ or NMN is pitched for a specific problem — including when it says nothing.

dosing

Dosing, safety & stacking

How much, when, what it interacts with, and the safety questions worth taking seriously.

fundamentals

The fundamentals

The core questions — whether it does anything at all, and what “anti-aging” is actually claiming.