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NAD+evidence-first

The NAD Review
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provider_review · verified 2026-07-31

MadeMed review

Two routes, two published floors, and a page that stops there

"From $199/mo" for the injectable and "From $269/mo" for the nasal spray are the entire contents of the NAD+ page — no dose, no strength, no states, no pharmacy.

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at_a_glance

price
"NAD+ Injectable — NanoNAD+ patented technology … From $199/mo" and "NAD+ Nasal Spray … From $269/mo", the two tiles that make up the NAD+ therapy page.
what you pay
Not knowable from the public site. Both published figures are floors and the page states no dose, no strength and no billing cadence.
pharmacy
Not named, and no 503A or 503B designation is published. MadeMed carries a LegitScript verification, which speaks to the seller rather than to the compounder.
states
Not published.
on our index
Ranked #5 of 19 on our NAD+ provider index.

verdict

The short version

MadeMed sells NAD+ two ways and publishes a figure for each: injectable from $199 a month, marketed as "NanoNAD+", and a nasal spray from $269. Publishing anything at all puts it ahead of a good deal of this category, and having genuinely different routes from one provider is useful. But both figures are "from" floors, and the NAD+ page is otherwise almost empty — two product tiles and a "Learn more" link, with no dose, no strength, no state availability, no pharmacy and no terms. The nasal spray at $269 is the most expensive NAD+ product on our index, for the route with the least human evidence behind it.

evidence

What the evidence for this route shows

Compounded NAD+ is not an FDA-approved product, and the route sold here has no randomised human trial behind it: there is no published study showing that subcutaneous or intranasal NAD+ raises blood NAD+ in people, let alone that it improves energy, focus or any aging endpoint. What the clinical literature actually supports is the oral precursor NR, which does raise blood NAD+ in controlled trials — a different molecule by a different route. "NanoNAD+ patented technology for superior absorption" is a marketing claim about a delivery format, not a finding: a patent is a description of an invention, not evidence that it works, and no absorption study is cited on the page. The nasal spray at $269 is the most expensive product on our index for the route with the least human data.

pricing

What it actually costs

advertised
"NAD+ Injectable — NanoNAD+ patented technology … From $199/mo" and "NAD+ Nasal Spray … From $269/mo", the two tiles that make up the NAD+ therapy page.
you pay
Not knowable from the public site. Both published figures are floors and the page states no dose, no strength and no billing cadence.
the catch
Two floors and no ceiling. There is a second mechanism worth knowing about that the NAD+ page does not mention: MadeMed's weight-loss line, which we track separately, bills quarterly in a single lump — its "$239/mo" plan is charged as $717 every three months — and reaches its lowest advertised monthly figure only on a six-month commitment. Nothing on the NAD+ page says whether the same billing shape applies here, which is precisely the problem.

Other money you will meet

  • No billing cadence published on the NAD+ page
  • No shipping, consult or membership terms published on the NAD+ page

source :: read at mademed.com on 2026-07-31, in a browser that runs JavaScript.

fit

Who this is and is not for

Buy it if

  • You want injection and nasal spray from a single provider and want to switch between them later
  • You want a floor price you can budget from before starting an intake
  • You are comfortable with a LegitScript-verified seller that publishes little else

Look elsewhere if

  • You need a firm number: both figures are floors, and what your dose costs is settled after intake
  • You want the nasal route at a sensible price — $269 is the highest on our board
  • You want to know which pharmacy fills it, or whether your state is covered
  • You want any product detail at all before committing: strength and dose are not published

included

What is inside the price

consult
Implied by the prescription model but not stated on the NAD+ page.
labs
Not mentioned.
follow-ups
Not mentioned.
human support
Not mentioned.
supplies
Not mentioned for the injectable.
shipping
Not mentioned on the NAD+ page.

the_knock

What they would rather you skipped

The NAD+ page is roughly a thousand characters long and two-thirds of that is product blurb. It publishes two prices and nothing else — no strength, no dose, no injection schedule, no billing cadence, no state list, no pharmacy, no cancellation terms. That is not an oversight on a small page; it is the whole page. A reader who wants to know what $199 a month buys them has no way to find out short of entering an intake, and the one structural fact we do know about how MadeMed bills — a quarterly lump on its weight-loss line, with the best rate reserved for a six-month commitment — is the kind of thing that turns a "from $199/mo" into a $597 charge. The claim that a patented nanoformulation delivers "superior absorption" is asserted with no study behind it, on a route with no human absorption data of any kind.

And the rest

  • Both prices are floors, with no ceiling, no dose and no strength published
  • The nasal spray at $269 is the most expensive NAD+ product on our index
  • No billing cadence published, against a sibling product line that bills quarterly in a lump
  • No pharmacy, no 503A/503B designation, no state list, no terms on the product page
  • MadeMed pays us a commission if you start care through this page

tools

Work out your own number

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Every figure on this page was read on MadeMed’s own site on 2026-07-31 in a browser that runs JavaScript, and prices change without notice. Compare it against the rest of the field on our NAD+ provider index, or read every provider review.

Medical disclaimer: This content is for general educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional before starting, stopping, or changing any treatment.